Lesson 20, Topic 3
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  • Definitive Diagnosis:
    • absence of circulating microfilariae
    • positive immunodiagnostic test
  • Presumptive Diagnosis:
    • absence of circulating microfilariae
    • radiographs supportive of pulmonary artery and pulmonary parenchymal changes due to heartworm
  • Radiography:
    • right ventricular enlargement
    • dilation of the main pulmonary artery
    • enlargement, tortuosity and/or pruning of the pulmonary arteries
    • pulmonary parenchymal changes of an alveolar pattern (coalescent fluffy [patchy] regions adjacent to pulmonary arteries)
    • may see consolidation of lung lobes (so-called pulmonary eosinophilic granulomatosis)
  • Electrocardiography:
    • usually signs of right heart enlargement as described for microfilaremic heartworm disease
  • Blood Work:
    • Hematology: eosinophilia – common; basophilia – common
    • Immunodiagnostics: IFA, ELISA, Agglutination Test