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Cardiovascular Physiology and Pathophysiology
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Physiology
Structure and Function4 Topics -
Lymphatics and Edema Formation
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The Microcirculation
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Vascular Control3 Topics
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The Cardiac Cycle
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Determinants of Myocardial Performance7 Topics
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Neuro-Control of Heart and Vasculature4 Topics
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Electro-Mechanical Association4 Topics
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Electrical Side of the Heart4 Topics
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PathophysiologyDefining Heart Failure
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Causes of Heart Failure
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MVO2 and Heart Failure
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Cardiac Output and Heart Failure7 Topics
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Compensation for Circulatory Failure
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Vascular Tone in Heart Failure
Lesson 9,
Topic 2
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Electrical System of the Heart
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The role of the electrical system of the heart is:
- To maintain an adequate heart rate (proportional to the energy expenditure of the body)
- To coordinate the contraction of the atria and the ventricles in series
- To coordinate the simultaneous contraction of the two atria and subsequently the two ventricles (especially the ventricles)
Components of the electrical system in the heart
The Sino-Atrial (SA) Node:
- It is the command center for the coordination of all electrical activity
- The cells of the SA node have the property of automaticity (depolarizing spontaneously)
- These cells are under the influence of the autonomic nervous system
- The sympathetic system (beta-adrenergic stimulation) increases the firing rate of the SA node
- The parasympathetic system (acetylcholine stimulation) decreases the firing rate of the SA node
The Atrio-Ventricular (AV) Node:
- It serves as the gateway for electrical transmission between the atria and the ventricles
- It serves to insert an appropriate delay between atrial and ventricular contraction
- It prevents the ventricles from being activated too rapidly in cases of excessively rapid atrial activation
Bundle of His:
- A short segment of “electrical highway” connecting the AV node and the bundle branches
Bundle Branches:
- Left and right bundle branches deliver the electrical current from the bundle of His to the left and right ventricle, respectively
Purkinje Fibers:
- The bundle branches terminate in the myocardial tissue along the endocardium in Purkinje fibers