Lesson 18, Topic 6
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Prognosis

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  1. Asymptomatic individuals
    1. response to therapy is excellent
  2. Individuals with mild to moderate disease
    1. response to therapy is usually excellent
    2. although all worms are rarely killed, the marked reduction in parasite burden results in a marked improvement of pulmonary function
  3. Individuals with severe right heart failure
    1. one can be cautiously optimistic about the response to therapy. With support for heart failure, and using a three injection protocol of melarsomine to promote a graded worm kill effect, most individuals usually respond
  4. Individuals with severe chronic interstitial disease
    1. may have persistent residual cough